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Otects the cells from anoikis and the receptor and signal transduction

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Otects the cells from anoikis and the receptor and signal transduction pathway through which IGFs act.ResultsModel of anoikis in oestrogen-responsive breast cancerMCF-7 cells were added to uncoated or poly-HEMAcoated culture wells to prevent cell attachment [26]. After 24 h, cells in the poly-HEMA-coated wells grew as rounded cells in suspension (Fig. 1). To investigate if the unattached MCF-7 cel
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Ecent studies using phosphomimetic mutants of CNKSR1 have identified phosphorylation sites

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Ecent studies using phosphomimetic mutants of CNKSR1 have identified phosphorylation sites in the scaffold critical for nuclear translocation and activation of MAPK pathway genes [21]. However, to date all CNKSR1 analysis in the context of pancreatic cancer has been performed at a molecular level with no translational or clinically oriented application. Using pancreatic tumor tissues from three in
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Erved association of CNKSR1 expression and survival outcome suggests scaffolding proteins

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Erved association of CNKSR1 expression and survival outcome suggests scaffolding proteins of the RAS-MAPK pathway may account, in part, for the observed heterogeneity of PDAC biology, and clinically may aid in improved future patient stratification.MethodsStudy participants and tissue microarray (TMA) compositionDe-identified cancer tissues included in this analysis were confirmed to be pancreatic
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The OPN KO animals had a 30 decrease in fracture toughness, and

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Disorders, cancers (VLPs targeting self-antigens) . Particulate delivery systems similar in sizeDisorders, cancers (VLPs targeting self-antigens) . Particulate delivery systems similar in size and geometry to pathogens, such as VLPs, are efficiently uptaken by professional antigen-presenting cells for both MHC classWJV|www.wjgnet.comAugust 12, 2015|Volume 4|Issue 3|Trovato M et al . Vaccine
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