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Com/1471-2105/12/S5/SPage 17 of30. Tibshirani R, Hastie T, Narasimhan B, Chu G: Diagnosis of multiple cancer types by shrunken centroids of gene expression. Proc Natl Acad Sci U S A. 2002, 99(10):6567-6572. 31. PLINK. [http://pngu.mgh.harvard.edu/purcell/plink]. 32. Burton P: Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 2007, 447:661-678.

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